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KMID : 0359720120300010057
Journal of the Korean Neurological Association
2012 Volume.30 No. 1 p.57 ~ p.59
Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment
Cho Jae-Wook

Jung Na-Yeon
Bae Jin-Won
Kim Dae-Jin
Lee Jae-Hyeok
Takashi Kanbayashi
Abstract
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s. Recent papers have addressed the response to immunotherapies in NC, with challenging results. We report a case of late-onset NC in a patient who did not benefit from early intravenous high-dose immunoglobulin (IVIg) therapy. This is the first reported attempt at using IVIg to treat an NC patient in Korea.
KEYWORD
Narcolepsy with cataplexy, Intravenous immunoglobulins
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